A generative data-visualisation of all the scientific evidence for popular health supplements by David McCandless and Andy Perkins.
I’m a bit of a health nut. Keeping fit. Streamlining my diet. I plan to live to the age of 150 in fact. But I get frustrated by constant, conflicting reports and studies about health supplements.
Is Vitamin C worth taking or not? Does Echinacea kill colds? Am I missing out not drinking litres of Goji juice, wheatgrass extract and flaxseed oil every day?
In an effort to give myself a quick reference guide, I dove into the scientific evidence and created a visualization for my book. And then worked with the awesome Andy Perkins on a further interactive, generative “living image”.
Play with interactive version | See the still image
This visualisation generates itself from this Google Doc. So when new research comes out, we can quickly update the data and regenerate the image. (How cool is that??) Hopefully then this should be a useful web resources for years to come.
About the image
This image is a “balloon race”. The higher a bubble, the greater the evidence for its effectiveness. But the supplements are only effective for the conditions listed inside the bubble.
You might also see multiple bubbles for certain supps. These is because some supps affect a range of conditions, but the evidence quality varies from condition to condition. For example, there’s strong evidence that Green Tea is good for cholesterol levels. But evidence for its anti-cancer effects is conflicting. In these cases, we give a supp another bubble.
The evidence
We only considered large, human, randomized placebo-controlled trials in our data scrape – wherever possible. No animal trials. No cell studies. Many of the health claims made by the $23 billion supplements industry are based on non-human trials. We wanted to cut through that.
This piece was doggedly researched by myself, and researchers Pearl Doughty-White and Alexia Wdowski. We looked at the abstracts of over 1500 studies on PubMed (run by US National Library Of Medicine) and Cochrane.org (which hosts meta-studies of scientific research). It took us several months to seek out the evidence – or lack of.
You can see our key results in this spreadsheet. (It’s the same spreadsheet that generates the interactive image).
Generation Game
This is our first interactive piece here on Information Is Beautiful. We’ll be doing more generative pieces over the next few months so stay tuned!
Updates
UPDATE 1: 6th Mar 2010 - We’ve updated the spreadsheet (changes in bold) and the viz after great feedback and new evidence and corrections from our amazing visitors. Thank you all so much.
Quick summary: We’ve added CoQ10, cocoa, capsaicin, L-Lysine and hyaluronic acid to the chart. And adjusted entries for Magnesium, Tumeric and Omega 3 (part of a massive downgrade of Omega 3 in fact). Read the change-log for full details
UPDATE 1: 10th Mar 2010 - Omega 3 has been downgraded in almost every category. See the spreadsheet (changes in bold) for more details.
See the visualisation | Check out the spreadsheet
Feed Us Back
As ever, we welcome your thoughts, crits, comments, corrections, compliments, tweaks, new evidence, missing supps, and general feedback. Thank you!




165 Comments
What a great representation of information a lot of people want and need, I am glad I “stunbled upon this one”
This post is so COOL! I love the “ballon race” that shows the effectiveness of health supplements/products. Can’t denied that Green Tea is good for health. I drink them everyday.
That is amazing! You used the Cochrane reviews, clearly… they have an incredible set of reviews on the care of pregnant and laboring women. It would really help families make good decisions about their health care, and doctors make better decisions about their routines and protocols, to see a chart like this on medical interventions and other aspects of care. Like ultrasound, denying food and drink in labor, walking to induce labor, etc.
Perhaps the size of the bubble could show its balance of risk to benefit; larger bubbles more helpful/ harmless. The book A Guide to Effective Care in Pregnancy and Childbirth by Enkin et al summarizes the Cochrane database on this topic, and even has a series of charts in the back that could easily be turned into an interactive chart like this.
Whaddaya think? Heck, I’d even be willing to do it myself, if I could figure out how you did it…
Nice work!
I believe “polphenols” should be “polyphenols”.
Please consider adding Meltonin both for sleep and cancer support. It is widely used and has a lot of data to back it.
Many kind thanks for your considerable efforts– your collation serves as a credible reference, yes, but it’s best used as a springboard to our own individual research.
A couple of suggestions that might warrant inclusion on your list:
1. GABA, for stress/anxiety. Efficacy via oral admin has been controversial, as GABA is not believed to cross the blood/brain barrier. However, here’s an abstract (human clinical) that suggests otherwise:
http://www.ncbi.nlm.nih.gov/pubmed/16971751
2. L-Carnosine. At present, I’ve no idea if any human trials have been conducted, but I figure you guys’ll dig up the latest dirt.
http://www.ncbi.nlm.nih.gov/pubmed/20552048
Carnosine’s ability to react with MG and possibly other deleterious carbonyl compounds, and scavenge various ROS, may account for its protective ability towards ischemia and ageing.
I agree that melatonin should be added for sleep. I’m not sure about cancer… I think I read there’s a slight decrease on onset of certain types of skin cancer?
Regardless, please keep updating this!
This is pure genius! Think of the applications for presenting data in a more visual format. The fact that you can generate this from Google docs. frankly amazes me. What kind of code do you use to generate the image?
I am an omega 3 person myself. And, I have also stumbled upon the ganoderma / reishi mushroom. I am all for natural herbs and plants.
Love it – any data on rhodiola?
Really, Omega 3 Supplementation for depression is below the “worth it” line? Omega 3 supplements have received empirical evidence regarding long-term effectiveness that is at least comparable to the long-term effectiveness of any antidepressant medication. Combined with other lifestyle changes, including exercise, improved sleep hygiene, and increased time spent socializing, omega 3s easily beat antidepressant meds in the long-run.
Sincerely,
A Clinical Psychology Ph.D. student (one year from internship and two years from attaining the Ph.D.)
Its great representation but I couldnt find ‘Resveratrol’ in it. I really wanted to see how that did it with the hype and evidence.
Beautiful!
Can you please add the date of the latest update (including the year) to the visualization?
Thx!!
What about Grape(fruit) seed extract (GSE). I have been told to use it for boosting immune system while traveling etc… The people I traveled with (and myself) found it useful but that may have been more placebo than anything else (either way it worked). Are there any studies on it?
Thanks for being such a health nut that drives you to present this data so beautifully and usefully. But to keep healthy is not so good to be nut, so take it easy. Apart from nutrition, a peaceful mind in needed to reach a long life.
Another ingredient for your kind consideration: cordyceps sinesis
Long live Information is Beautiful!
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